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Update date: July 20, 2026

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Human meningiomas arise from developmental meningeal mosaicism

Human meningioma mosaicism

Matched tumor, blood, and normal meninges show low-VAF driver mosaicism in most patients, but direct arachnoid sampling was not possible and higher-grade tumors were underrepresented.

Crossed laser phase plate for CryoEM

A crossed dual-cavity phase plate improved low-frequency cryo-EM contrast, yet ghost artifacts and phase-fitting bias still need broader quantification before routine use.

Mature plant chloroplasts form reversible gyroid cubic membranes

Reversible gyroid chloroplast membranes

Mature Arabidopsis chloroplasts can reversibly shift into a gyroid-like membrane state at night and back with light, although topology assignment still relies partly on model fitting.

Reversible Opto-Chemical activation of KRASG12V signaling with near single-cell precision

Reversible KRASG12V activation

Sustained plasma-membrane recruitment of KRASG12V drove reversible crypt expansion in intestinal organoids, while short or withdrawn activation reduced the remodeling effect.

DEC1 Regulates Human β Cell Functional Maturation and Circadian Rhythm

DEC1 and human β-cell maturation

Removing DEC1 impaired human stem-cell–derived β-cell maturation, glucose-stimulated insulin secretion, and circadian rhythm, and metabolic flux rescue supports a clock-to-metabolism link despite incomplete locus-level proof.

OxyBLI: A Genetics-Based Approach for In Vivo Real-Time Visualization of Tissue Oxygenation Dynamics

OxyBLI tissue oxygen dynamics

OxyBLI tracks rapid tissue oxygen changes in living mice with cell-type targeting, but the readout is relative rather than absolute PO2 and depends on ATP and oxygen consumption.

Exploring the diversity and spatial distribution of Anopheles mosquitoes and their associated Plasmodium species in Tanzania using the ANOSPP amplicon panel

ANOSPP mosquito and Plasmodium mapping

ANOSPP sharpened species calls across Tanzanian mosquitoes and parasite detections, but morphology error, sentinel-site sampling, and DNA-based parasite signals still limit transmission-stage inference.

Spatial Compartmentalization of TCR Repertoires Between Primary Melanomas and Sentinel Lymph Nodes Reveals Distinct Clonal Architectures and Shared Antigen Recognition

Melanoma and sentinel-node TCR repertoires

Paired melanoma and sentinel-node repertoires show compartment-specific selection footprints and recurrent motif communities, but most antigen matches remain unannotated.

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