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    Create Graphs (from provided paper data): Trial phase + Target distribution
    Used sources (raw distributions explicitly provided in your dataset):
    • Trial phase distribution from a registry-based analysis of digestive-system cancer vaccine trials: 10.2147/CMAR.S561298
    • Target distribution from a registry-based analysis of the global CAR-T trial landscape (top targets): 10.1186/s40364-026-00910-6
    Note: The provided excerpts include trial phase counts for the cancer vaccine review, and target rankings for the CAR‑T review. The CAR‑T excerpt does not provide phase-by-phase counts, and the cancer-vaccine excerpt does not provide a complete numeric target histogramβ€”so the graphs below use only what is explicitly available.
    The excerpt specifies the top target names (e.g., CD19, TNFRSF17, CD22…) but does not provide the numeric target frequencies needed for a true count plot. The bar heights above are used only to present an ordered β€œtop list” view; they are not trial counts.
    Evidence notes & limitations (skeptical reading)
    • Trial phase plot uses explicitly provided phase counts (Phase I, Phase I/II, Phase II, Late-stage) from a registry-based analysis of interventional digestive-cancer vaccine trials. The excerpt does not provide late-stage phase breakdown beyond a single β€œlate-stage” bucket.
    • CAR‑T status plot uses explicit trial-status percentages (ongoing/planned/completed/terminated/closed) from a global CAR‑T trial landscape analysis based on INFORMA data and deduplication to 1,908 trials.
    • CAR‑T target β€œtop list” plot shows target names only; no numeric frequencies were provided in the excerpt. Therefore, the visualization cannot support claims about relative prevalence by target.
    • Registry-based summaries can be affected by coverage limits, reporting changes over time, and registry-specific indexing/deduplication rules. The excerpt explicitly notes reliance on single registries and lack of public deposition of underlying trial-level data.
    • For the vaccine-trial phase plot, the excerpt similarly indicates descriptive, registry-based meta-analytic framing and potential reporting bias.


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    Updated: April 30, 2026

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