| 1 |
Miller |
Building a Safe and Transparent Workflow for Large Language Model LLM-Assisted Clinical Trials and Prediction Models |
2025 |
10.7759/cureus.92571 |
Cureus Technical Report |
Proposes a seven step workflow (scope, retrieval augmented review, benchmarking, audit trail, expert gates, disclosure, privacy) and provides reusable checklists mapping to CONSORT-AI SPIRIT-AI TRIPOD+AI and PRISMA to support LLM use in clinical research while preserving transparency and auditability. |
Moderate |
| 2 |
Sturm |
The Italian Portrait of Laboratory Information Systems in Pathology The Ones We Have and the Ones We Would Like |
2025 |
10.3390/jpm15110517 |
Journal of Personalized Medicine |
Comparative analysis of three LIS platforms in Italian pathology with evaluation of integration, digital reporting, traceability, and compliance to standards such as GDPR and ISO 15189; highlights tradeoffs across Armonia, Pathox Web, and WinSAP 3.0. |
Moderate |
| 3 |
Raine |
Automated data collection from an electronic medical record for a prospective real-world study in patients with retinal disease VOYAGER |
2025 |
10.1177/17407745251358235 |
Clinical Trials Journal |
Pilot EMR-to-EDC integration prepopulated many eCRF fields, reduced queries, and saved estimated staff time; shows feasibility and operational benefits while noting pull-through of irrelevant data as a challenge. |
Moderate |
| 4 |
Hirsch |
Safeguarding Open Science from exploitative practices |
2025 |
10.1371/journal.pmed.1004851 |
PLOS Medicine |
Argues that open science must include safeguards because freely available data can be exploited; recommends practical governance and technical controls to reduce integrity risks from open sharing. |
Strong |
| 5 |
Rocca |
Identifying genomic data use with the Data Citation Explorer |
2024 |
10.1038/s41597-024-04049-7 |
Scientific Data |
Describes the Data Citation Explorer (DCE) to automatically discover literature that used genomic data without formal citation; shows improved coverage and metadata enrichment compared to manual curation and benefits for data generators. |
Strong |
| 6 |
Meyer |
The Advanced Confidentiality Engine as a Scalable Tool for the Pseudonymization of Biomedical Data in Translational Settings Development and Usability Study |
2025 |
10.2196/71822 |
Journal of Medical Internet Research |
Introduces ACE an open source pseudonymization service supporting multiple algorithms, fine-grained access control, domain structuring, audit trail and throughput experiments demonstrating ~6000 transactions/sec under tested workloads. |
Strong |
| 7 |
Zarei |
A NoSQL document based eCRF system for study of vaccines with variable adverse events case study on COVID19 vaccines |
2025 |
10.1038/s41598-025-05746-y |
Scientific Reports |
Proposes a document oriented eCRF for variable adverse event reporting in vaccine studies; compares performance with relational models and reports improved response time and flexibility for unstructured case report data. |
Moderate |
| 8 |
Various |
Data and methods papers and selected database/dataset entries (selected examples) |
2016-2025 |
N A |
BioStudies and others |
Includes BioStudies dataset E GEOD 83275 (table grapes transcript profiling) demonstrating how dataset metadata can be surfaced; see dataset link for experiment-level details and files. |
Weak to Moderate |