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"I think it's much more interesting to live not knowing than to have answers which might be wrong."
- Richard Feynman
Quick Answer
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Answer: Frederick Griffith performed his classical bacterial 'transformation' experiment in 1928
Long Answer
Visual answer: When did Griffith do his experiment?
Compact evidence and context
Frederick Griffith's classic experiment demonstrating bacterial 'transformation' was published in 1928. In that paper Griffith reported that material from heatβkilled virulent Streptococcus pneumoniae converted live nonβvirulent bacteria into virulent forms β an observation later foundational to identifying DNA as the genetic material
One-line historical timeline (for context)
Direct citation (source for year)
Primary historic source (Griffith's paper, 1928):
Confidence, limitations, and what would change the conclusion
Confidence: high that the experiment was conducted/published in 1928 β this is the standard, wellβdocumented historical fact cited in primary historical literature and textbooks.
What would change this conclusion: discovery of an earlier, authenticated, primary account of the same experiment with a different date (none is known). Secondary retellings do not alter the publication year of Griffith's original work.